Protection against systemic candidiasis in mice immunized with secreted aspartic proteinase 2
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چکیده
منابع مشابه
Secreted aspartic proteinase family of Candida tropicalis.
Medically important yeasts of the genus Candida secrete aspartic proteinases (Saps), which are of particular interest as virulence factors. Like Candida albicans, Candida tropicalis secretes in vitro one dominant Sap (Sapt1p) in a medium containing bovine serum albumin (BSA) as the sole source of nitrogen. Using the gene SAPT1 as a probe and under low-stringency hybridization conditions, three ...
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Secreted aspartyl proteinases are putative virulence factors in Candida infections. Candida albicans possesses at least nine members of a SAP gene family, all of which have been sequenced. Although the expression of the SAP genes has been extensively characterized under laboratory growth conditions, no studies have analyzed in detail the in vivo expression of these proteinases in human oral col...
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ژورنال
عنوان ژورنال: Immunology
سال: 2004
ISSN: 0019-2805,1365-2567
DOI: 10.1111/j.1365-2567.2004.01819.x